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text model · Mistral · Windows

Can I run Mistral Nemo 12B on AMD Ryzen AI Halo (128GB)?

Compatibility verdict VRAM threshold engine
Yes, it runs GPU accelerated ~24 tok/s est.

Yes. Mistral Nemo 12B runs on AMD Ryzen AI Halo (128GB) at Q4_K_M (~8.6 GB of ~96 GB usable).

Needs ~8.6 GB Device usable ~96 GB

Runs at Q4_K_M using ~8.6 GB of ~96 GB usable. You have room for FP16 for higher quality.

That figure is at a 4k context and moves about ±15% as context length changes. AMD Ryzen AI Halo (128GB) leaves ~87.4 GB of headroom, room to step up to FP16 for higher quality.

Q4_K_M needed
~8.6 GB
Usable on device
~96 GB
Device memory
128 GB
Best quant
Q4_K_M
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Which quant fits

Quant ladder vs ~96 GB usable
Q2_K
~6.7 GB
Q3_K_M
~7.6 GB
Q4_K_M
~8.6 GB
Q5_K_M
~10.3 GB
Q6_K
~11.6 GB
Q8_0
~13.7 GB
FP16
~26 GB
The line marks AMD Ryzen AI Halo (128GB)'s ~96 GB budget; rungs past it are too large.

Running cost · estimate

Power & economics est.
Power draw
~120 W
Electricity / 1M tokens
~$0.21
Pays for itself after
~13,790M tok

At ~$0.15/kWh and the estimated ~24 tok/s, a million generated tokens costs about $0.21 in electricity. Versus a hosted API at ~$0.5 per million tokens, the ~$3,999 AMD Ryzen AI Halo (128GB) pays for itself after roughly 13,790 million tokens, so local hardware is mostly a fixed cost, not a per-token one. TDP is the peak draw, so this is an upper bound. Assumptions.

Run it

Install commands Windows

Pick your tool. All 3 load the same Q4_K_M weights.

Ollama
$ ollama run mistral-nemo:12b
llama.cpp
$ llama-cli -hf bartowski/Mistral-Nemo-Instruct-2407-GGUF:Q4_K_M
LM Studio
$ lms get bartowski/Mistral-Nemo-Instruct-2407-GGUF
Model Mistral
Parameters
12.2B
Q4_K_M size
6.96 GB
Q8_0 size
12.13 GB
Context
128k
Ollama tag
mistral-nemo:12b
Full Mistral Nemo 12B requirements →
Device Windows
Memory
128 GB unified
Usable for weights
~96 GB
Power draw
~120 W
Best runtime
llama.cpp (Vulkan/ROCm) / LM Studio
Best models for AMD Ryzen AI Halo (128GB) →

You could also run

Run Mistral Nemo 12B on other hardware

FAQ

Can AMD Ryzen AI Halo (128GB) run Mistral Nemo 12B?

Yes. Mistral Nemo 12B runs on AMD Ryzen AI Halo (128GB) at Q4_K_M (~8.6 GB of ~96 GB usable).

How much memory does Mistral Nemo 12B need?

AMD Ryzen AI Halo (128GB) has room to spare. At Q4_K_M the weights are ~6.96 GB; with KV cache and runtime overhead, budget ~8.6 GB at a 4k context.

What is the best tool to run Mistral Nemo 12B on Windows?

LM Studio for a simple setup; Ollama (CUDA) for the most speed. AMD GPUs run via Vulkan/ROCm at roughly half CUDA throughput. NVIDIA is the smooth path on Windows.

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Sources

Weights are measured from GGUF files; KV cache and overhead are computed, so totals can vary ~15% with context and runtime. Any tok/s is a bandwidth estimate. See methodology.